Group 18: FINDING GENE PATTERNS IN BREAST CANCER DATA

Introduction:

Question: Which genes are differentially expressed in different subtypes of cancer?

EXPLORATORY ANALYSIS AND TIDY:

Cleaning procedure

EXPLORATORY ANALYSIS AND TIDY:

Ratio between male and female

EXPLORATORY ANALYSIS AND TIDY:

Age of female patients stratified by cancer status

DESEQ ANALYSIS:

PCA Analysis:

Here is an analysis of PCA plots showing the scree and cumulative variance explained.

The high dimentionality required to explain 85% of the variability of the data shows that cancer analysis is a difficult task.

PCA Analysis:

• The highlighted genes for each PC might be linked to specific biological pathways or processes, as they represent the main drivers of variance for the data.
• The PCA shows significant overlap between “TUMOR FREE” and “WITH TUMOR”, indicating no clear separation of cancer statuses.